A nonlocal observation operator has been developed to assimilate GPS radio occultation (RO) refractivity with WRF 3DVAR.For simplicity, in the past GPS RO refractivity was often assimilated using a local observation operator with the assumption that the GPS RO observation was representative of amodel local point.Such an operator did not take into a
Abstract Background Vector control remains the primary defense against dengue fever.Its success relies on the assumption that vector density is related to disease transmission.Two operational issues include the amount by which mosquito density should be reduced to minimize transmission and the spatio-temporal allotment of resources needed to reduce
Obesity and metabolic syndrome reflect the dysregulation of molecular pathways that control energy homeostasis.Here, we show that the p75 neurotrophin receptor (p75NTR) controls energy expenditure in obese mice on a high-fat diet (HFD).Despite no changes in food intake, p75NTR-null mice were protected from HFD-induced obesity and remained lean as a